Karen Read and John O'Keefe: Inside evolution of Boston murder mystery since July mistrial

Karen Read, the woman accused of killing her Boston cop boyfriend during a January nor’easter, is set to go on trial for a second time this week after her first prosecution ended with a hung jury.

Read, 45, is charged with second-degree murder, manslaughter and leaving the scene of a deadly accident in connection with John O’Keefe’s death on Jan. 29, 2022. He was 46 and found in the snow outside another police officer’s house hours after a group of people went there for an after-party to cap off a night out drinking.

She was originally charged with manslaughter – typical in a deadly hit-and-run case – but authorities later tacked on the murder charge.

KAREN READ UPDATE: FIRED LEAD INVESTIGATOR ON WITNESS LIST FOR 2ND TRIAL IN BOSTON COP JOHN O’KEEFE’S DEATH

Through her first trial and in multiple media interviews afterward, she maintained her innocence and claimed someone else killed O’Keefe.

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Joseph Giacalone, a former NYPD sergeant and a criminal justice professor at Penn State-Lehigh Valley, told Fox News Digital he thinks prosecutors will have a hard time getting a conviction after the first case fell apart.

The first trial saw allegations of a police cover-up, the arrest of an online blogger accused of intimidating witnesses, the firing of the lead investigator and lingering questions about how O’Keefe died.

KAREN READ’S 2ND MURDER TRIAL SET TO START IN DEATH OF BOYFRIEND COP: WHAT TO KNOW

Prosecutors allege that Read backed into him with her Lexus SUV, then drove away, leaving him to die in the snowstorm.

An autopsy found the cause of his death to be blunt-force trauma to the head and hypothermia. O’Keefe had skull fractures, brain bleeding, swollen black eyes and cuts to his right arm, but the forensic pathologist held off on calling it a homicide, leaving the manner of death undetermined.

Dr. Daniel Wolfe, an expert witness, testified that the damage to the rear end of Read’s vehicle was not consistent with striking a human head or arm. Prosecutors are seeking to have his testimony precluded the second time around.

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His name remained on a 150-person witness list unveiled Monday, along with that of Michael Proctor, the former lead investigator who was fired from the Massachusetts State Police this month.

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Read the witness list: Mobile users click here

The following is a timeline of key events in the case:

Jan. 28, 2022

Read and O’Keefe went out in Canton, Massachusetts, a suburb of Boston about 15 miles from the city.

Although text messages introduced at trial show they had argued that morning, they went out together around 9 p.m. at C.F. McCarthy’s, an Irish bar. Around 11, they met friends and acquaintances at the Waterfall Bar and Grille. The bar closed at midnight.

JUROR IN KAREN MISTRIAL JOINS HER DEFENSE TEAM FOR RETRIAL

Jan. 29, 2022

Then-Boston Police Officer Brian Albert invited a group of people to his house on Fairview Road for an after-party when the bar wrapped up service. This could be the last time O’Keefe was seen alive in public.

JUROR IN KAREN MISTRIAL JOINS HER DEFENSE TEAM FOR RETRIAL

Early hours of Jan. 29

• 12 a.m.: O’Keefe and Read are invited over to Albert’s house and given directions. But witnesses have testified they never came inside.
• 12:37 a.m.: Read allegedly leaves a voicemail with an expletive for O’Keefe, saying, “John, I … hate you.” She was later accused of hitting him at about 24 mph after backing up 60 feet in her vehicle.
• 2:27 a.m.: Jennifer McCabe allegedly looks up on Google how long it takes to die in the cold. She later testified that she did the search at Read’s request.
• 6 a.m.: Read returns to the Alberts’ home with McCabe and another person, and they call 911 from outside, where O’Keefe was found dead, according to a synopsis from CourtTV, which streamed the first trial.
• 6:23 a.m.: McCabe uses her phone to search for information on dying in the cold for a second time.

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Feb. 2, 2022

Read was arrested on hit-and-run and manslaughter charges.

June 9, 2022

A superseding indictment accused Read of second-degree murder.

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April 16, 2024 to July 1

Read’s first trial stretched on for weeks and ended with a hung jury. Judge Beverly Cannone declared a mistrial.

Prosecutors accused Read of a drunken hit-and-run. Her defense argued that O’Keefe had been attacked inside the home and suffered injuries to his arm caused by a dog before being carried outside and left in the storm.

March 19, 2025

After a months-long internal investigation into the lewd text messages he sent about Read in the initial investigation, Proctor was fired from the Massachusetts State Police after a 12-year career.

March 31 

On the eve of jury selection for Read’s second trial, Cannone released several impactful rulings on the case.

She rejected the defense’s attempt to have a former FBI agent testify about failures to meet police protocol with the initial investigation and limited the scope of arguments the defense would be allowed to raise regarding potential third-party culprits, including Albert and ATF Agent Brian Higgins, both of whom were present at both the Waterfall bar and Albert’s house the night O’Keefe died.

The witness list also revealed Proctor would take the stand, even after his firing, and so would Aidan Kearney, a local blogger and prominent Read supporter who has been accused of witness intimidation.

April 1

Jury selection in Read’s second trial kicked off in Dedham, Massachusetts.

The Associated Press contributed to this report.